The most reasonable way to get your desired molecules.

Mcule provides a quick, easy and effective solution for your drug discovery needs. Challenge us!

1. Discovery

   • database of commercially purchasable compounds curated with MAC technique (see our poster)
   • flexible, integrated screening workflows with various tools
   • molecule collection management (hit lists, libraries)

2. Consultancy

   • improve your in-house drug discovery workflow
   • molecular modeling service (docking, pharmacophore searching, QSAR, diversity selection)
   • hit identification and lead optimization using experimentally validated processes
   • extension of your compound library with just the necessary new compounds

3. Delivery

   • single contact to multiple suppliers
   • one-click ordering of large collection of molecules
   • fast, single-package "home delivery" service

How can mcule help you?

• providing a platform for collaborative/multisite drug discovery projects
• effective way to identify new drug candidates using mcule’s virtual screening tools
• order compounds from various suppliers with a single click

Why mcule?

• cost-effective: no need to invest in computationally intensive IT infrastructure
• integrated: already integrated environment of various commercial and open source virtual screening tools
• secure: we apply the latest industry standards in security and privacy
• productive: more discovery projects per year for the same effort

Publications and Papers

• one of the largest docking-based virtual screenings ever yielded novel histamine H4 receptor chemotypes (J. Med. Chem. 2008, 51, 3145-53)
• experimental validation of our GPCR fragment library design process yielded 100% hit rate (Poster at ACS 2012 San Diego)
• Novel JAK1 inhibitors (see our presentation August 22, 2012 from 10:45 am to 11:15 am, Pennsylvania Convention Center, Room: 117)